https://github.com/Mottie/tablesorter/issues

My resolve based on using validating user-atributes data-*. jQuery support it atributes with function $(…).data()
So, now we can use for disabling sorting for this column and and some to set parser for this column (disable autodetect for parser type).

Code changed (jquery.tablesorter.js Version 2.0.3 ):

in function buildHeaders:
replace if(checkHeaderMetadata(this) || checkHeaderOptions(table,index)) this.sortDisabled = true;
by
if (checkHeaderMetadata(this) || checkHeaderOptions(table,index) || checkHeaderUserdata(this)) this.sortDisabled = true;

so add function checkHeaderUserdata before checkHeaderMetadata:
function checkHeaderUserdata(cell) {
return $(cell).data('tablesorter') === 'none';
}

in function buildParserCache:
before } else if((table.config.headers[i] && table.config.headers[i].sorter)) { insert next rows:
} else if ($($headers[i]).data('tablesorter') && $($headers[i]).data('tablesorter') !== 'none') {
p = getParserById($($headers[i]).data('tablesorter'));

And finally, html-parser:
ts.addParser({
id: 'html',
is: function (s) {
return //.test(s);
},
format: function (s) {
return s.toLowerCase().replace(//g, '');
},
type: 'text'
});